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Leaky gut in hypertension

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Leaky gut in hypertension

Dr Matthew Snelson, Monash University

2023 Vanguard Grant - One Year

Years funded: 2024 - 2024

High blood pressure is one of the main risk factors for cardiovascular disease. An important protective factor for high blood pressure is dietary fibre. Our team has determined this happens through the release of beneficial substances by gut microbes. These substances are key for improving the lining of the gut. In the absence of these substances, the gut may become leaky, when microbes and harmful microbial substances pass from the gut to our blood. This may result in an exaggerated inflammation in our body that contributes to the development of high blood pressure. So far, there is limited evidence available in animal models only.

Last updated12 March 2024