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Finding new ways to treat the causes of heart failure

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Finding new ways to treat the causes of heart failure

Dr Simon Foster, The Council of the Queensland Institute of Medical Research

2023 Future Leader Fellowship - Level 2 (Honorary)

Years funded: 2024 - 2027

New approaches are urgently required to overcome the lack of effective treatments for heart disease. This Future Leader Fellowship will find new ways to prevent cardiac fibrosis – or scarring – that occurs following heart injury. This scarring reduces the heart’s ability to contract, and can result in heart failure. Fibrosis is seen in >90% of heart failure patients, yet the changes in the heart that lead to fibrosis are poorly understood.

In this project, I will explore the communication between heart cells that controls heart function. By combining cutting-edge experimental methods with our unique model for the human heart, my team will discover the most important signalling processes controlling fibrosis. This will allow us to target these processes to improve heart function. Ultimately, this will lead to the development of better medicines for cardiac fibrosis and heart failure.

Last updated12 March 2024