I am
High blood pressure caused by hormonal imbalance - how common is it, and how do we detect it?
heartfoundation.org.au|Helpline 13 11 12

High blood pressure caused by hormonal imbalance - how common is it, and how do we detect it?

Dr Renata Libianto, Institution: Monash University

2018 Health Professional Scholarship

Years funded: 2019-2022


Hypertension affects millions of Australians and is a leading risk factor for heart attack and stroke. Most people with hypertension have "essential hypertension" (i.e. they have no reversible cause), but a proportion have a treatable secondary cause such as primary aldosteronism (PA). PA is condition of excess aldosterone production by the adrenal glands. Aldosterone is the hormone responsible for controlling blood pressure, and if produced in excess will have adverse effects on the cardiovascular system, above and beyond the effect which would be expected from just hypertension. If diagnosed, PA can be treated effectively with either surgery or with medication which blocks aldosterone action.

Despite increasing recognition of PA as a major public health issue, the rate of screening for PA in the primary care setting is low. One of the barriers to making a timely diagnosis of PA is the paucity of data on its exact prevalence, and therefore the cost-effectiveness of screening. Furthermore, we have few clinical markers to help distinguish PA from essential hypertension.

This project, therefore, aims to establish the prevalence of PA in primary care; and to identify early clinical features and cellular markers that may help distinguish PA from essential hypertension. The results from this study will further our understanding of the epidemiology and pathophysiology of PA, and may lead to a greater emphasis on the importance of PA in the management of hypertension.

This project is co-funded with NHMRC - National Health and Medical Research Council.

You might also be interested in

Research Directory

Research Directory

Altering the rehabilitation environment to improve stroke survivor activity (AREISSA)

Altering the rehabilitation environment to improve stroke survivor activity (AREISSA)

Assistant Professor Neil Spratt, Institution: The University of Newcastle...

Constructing Aboriginal health: a review of cardiovascular research, 1933-2014

Constructing Aboriginal health: a review of cardiovascular research, 1933-2014

Ms Joanne Luke, Institution: University of Melbourne...

Exercise and brain volume loss after stroke

Exercise and brain volume loss after stroke

Professor Amy Brodtmann, Institution: Florey Institute of Neuroscience and Mental Health...

Lipid disorders in patients at high cardiovascular disease risk

Lipid disorders in patients at high cardiovascular disease risk

Dr Esther Ooi, Institution: University of Western Australia...

Optimizing stroke therapy - advanced brain imaging and rapid restoration of blood flow to the brain

Optimizing stroke therapy - advanced brain imaging and rapid restoration of blood flow to the brain

Professor Bruce Campbell, Institution: University of Melbourne...

Promoting active, healthy lifestyles among women at key life stages

Promoting active, healthy lifestyles among women at key life stages

Associate Professor Verity Cleland, Institution: University of Tasmania...

Reducing population salt consumption in Victoria

Reducing population salt consumption in Victoria

Reducing population salt consumption in Victoria

Professor Bruce Neal, Institution: University of New South Wales...

Starting early – Increasing young children’s physical activity

Starting early – Increasing young children’s physical activity

Associate Professor Hayley Christian, Institution: University of Western Australia...

Strategies to optimise cardio-metabolic health

Strategies to optimise cardio-metabolic health

Associate Professor Melinda Carrington, Institution: Baker Heart and Diabetes Institute...

Research Directory

Research Directory

MyMarathon

MyMarathon

MyMarathon

The fundraising race where you set the pace. Run, jog or walk MyMarathon at your own pace during October....

Tenecteplase versus alteplase for stroke thrombolysis evaluation trial

Tenecteplase versus alteplase for stroke thrombolysis evaluation trial

Professor Mark Parsons, Institution: University of Melbourne...

Heart Health Check Toolkit

Heart Health Check Toolkit

Q&A with Dr Nathan Palpant

Q&A with Dr Nathan Palpant

Q&A with Dr Nathan Palpant

Deadly spider venom offers hope to people having a heart attack...

Health Professional Ambassador Program

Health Professional Ambassador Program

Health Professional Ambassador Program

Would you like to improve the cardiovascular health of your patients?...

2021 NSW CVRN Ministerial Awards for Cardiovascular Research

2021 NSW CVRN Ministerial Awards for Cardiovascular Research

Nominations are now open for the 2021 NSW Cardiovascular Research Network’s (CVRN) Ministerial Awards for Cardiovascular Research....

Beef recipes

Beef recipes

Beef recipes

Find heart healthy beef recipes....

WEBINAR | Navigating the latest updates on CVD prevention

WEBINAR | Navigating the latest updates on CVD prevention

COVID-19 info & FAQs

COVID-19 info & FAQs

COVID-19 info & FAQs

Information and FAQs about COVID-19 and heart disease....

Clinical resources: Coronary heart disease and mental health

Clinical resources: Coronary heart disease and mental health

The prevalence of depression is high in patients with coronary heart disease (CHD)....

Chicken recipes

Chicken recipes

Chicken recipes

Find heart healthy chicken recipes....

Healthy Bowl Recipes

Healthy Bowl Recipes

Healthy Bowl Recipes

Find more heart healthy bowl recipes in our Bowl Foods recipe booklet...

Fundraise to save Australian hearts

Fundraise to save Australian hearts

Fundraise to save Australian hearts

Join our community of fundraisers who are committed to taking action to fight heart disease....

For Professionals: Coronary artery calcium scoring

For Professionals: Coronary artery calcium scoring

The National Heart Foundation of Australia Position Statement: Coronary artery calcium scoring for the primary prevention of cardiovascular disease in Australia.¹...

Mexican spice blend

Mexican spice blend

Mexican spice blend

Blueberry cheesecake oats

Blueberry cheesecake oats

Blueberry cheesecake oats

10 minutes
Serves 2

Vegetarian lasagne

Vegetarian lasagne

Vegetarian lasagne

1 hour
Serves 6

Nutrition Evidence Summaries and Reviews

Nutrition Evidence Summaries and Reviews

Nutrition Evidence Summaries and Reviews

Tasty recipes to start the day | Breakfast Recipe Booklet

Tasty recipes to start the day | Breakfast Recipe Booklet

Tasty recipes to start the day | Breakfast Recipe Booklet

Have an easy and delicious start to your day. Get your free copy now....

More Australians die of Heart Disease than any other cause.

More Australians die of Heart Disease than any other cause.

More Australians die of Heart Disease than any other cause.

And the heartache lasts a lifetime. But you can help the Heart Foundation fund life-saving research to keep more families together....

Acute coronary syndromes (ACS) clinical resources

Acute coronary syndromes (ACS) clinical resources

Resources and clinical information for health professionals...

Nourishing chicken soup

Nourishing chicken soup

Nourishing chicken soup

1 hour
Serves Serves 6

Learning to listen to your heart

Learning to listen to your heart

Learning to listen to your heart

Guest blog by Heart Foundation of Australia Group CEO, Adjunct Professor John G Kelly AM...

Baking recipes

Baking recipes

Baking recipes

Find heart healthy baking recipes ...

What is atrial fibrillation?

What is atrial fibrillation?

What is atrial fibrillation?

Atrial fibrillation is a type of arrhythmia where your heart beats irregularly and fast....

Loaded veggie shepherds pie

Loaded veggie shepherds pie

Loaded veggie shepherds pie

1 hour
Serves Serves 4 (as a main meal)

Absolute CVD risk charts

Absolute CVD risk charts

Absolute CVD risk charts provide a visual tool to calculate CVD risk for use in practice in Australia....

Q&A with Professor Jonathan Golledge

Q&A with Professor Jonathan Golledge

A program to reduce complications and improve quality of life in people with blocked leg arteries...

Blood cholesterol

Blood cholesterol

Blood cholesterol

Keeping your blood cholesterol at a healthy level can help you reduce your risk of heart disease and other serious conditions. ...