Immune suppression after stroke
- Years funded:
- 2016 - 2019
Infection is highly prevalent and is one of the leading causes of death in stroke.
It is now recognised that stroke impairs the immune system, raising the possibility that reversing this impairment can decrease the rate of infection after stroke. Therefore, the focus of this project is to identify the signalling pathways that underlie abnormal immune function after stroke and also assess the potential of a novel pharmacological approach for reducing bacterial infection in stroke patients.
This research aims to delineate the basic biology underlying the altered immunity and control of bacterial complication after stroke.
A better understanding of this phenomenon will take us one very significant step closer to developing powerful and targeted treatment regimens for stroke patients, ultimately improving patient outcomes.
Dr Connie Wong