Defining the mechanisms controlling cardiac outflow tract formation

Years funded:
2016 - 2019

Abnormal formation of the cardiac outflow tract and cardiac valves lead to common malformations affecting over 2% of all births. As these complications have poor clinical outcomes and require ongoing medical treatment throughout life, new diagnostic and therapeutic tools are desperately required.

Dr Quenten Schwar's research program is aimed at identifying how a specific cell type, termed neural crest cells, control formation of the cardiac outflow tract and cardiac valves.

New information generated from this study stands to identify new molecular targets which may be used for predictive testing and regenerative therapies for these highly prevalent disorders. This data also stands to provide new insight toward regenerative therapies to replace heart muscle that is damaged as a result of common heart attacks.

Researcher Profile

Dr Quenten Schwarz

Institute: University of South Australia
Learn More