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Persistent cardiovascular effects of COVID-19
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Persistent cardiovascular effects of COVID-19

Dr Thomas Marwick, Institution: University of Melbourne

2020 CVD and COVID-19 Grant

Years funded: 2021-2021


Despite its onset as a respiratory infection by SARS-CoV-2, cardiovascular injury is common in COVID-19 disease, mediated by inflammation, heart muscle cell necrosis, blood clotting disorders and hypoxia. Recent reports have shown heart muscle damage in the majority of recovered patients after 2-3 months, and there are grounds to believe that cardiovascular complications could be an important source of ongoing disability in patients who recover from the acute illness. This study will document and characterise the presence of dysfunction of left and right heart chambers, blood vessels and disturbances of coupling between the heart and vessels, compared to control, population-based groups, identify the relative importance of cardiac vs other effects, and define the effect of this injury on functional capacity. It will begin the process of identifying management responses to this problem. This information will be of value in designing screening and management strategies in patients who have recovered from COVID-19.

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